Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (2025)

TL;DR

Advanced Trichology NutraM DHT Blocking Hair Serum was our favorite of the bunch, an easy-to-use leave-on that delivered impressive results. And if you have a sensitive scalp, consider Keeps 5% Minoxidil Foam, an effective option that doesn't cause skin irritation.

If you're dealing with hair loss and shedding, know you're not alone—roughly 40% of women will experience some level of hair loss by age 50. Board-certified dermatologist Dr. Peterson Pierre, M.D., notes that causes vary from stress and hormonal changes like pregnancy and even harsh hairstyles or products. The good news? A topical, over-the-counter treatment for hair loss can help turn things around—no prescription needed. Currently, only one topical ingredient is FDA-approved to treat hair loss: minoxidil. However, many other products with scalp-stimulating and DHT-blocking ingredients show promise.

We spent nearly 1,000 hours testing over 20 top-rated options in our New York City lab and at home for 12 weeks. Testers weighed the products' efficacy and results regarding new growth and a fuller hairline. Check out the winners below.

Our Top Picks

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What We Like

  • Easy-to-use dropper applicator

  • Dries quickly

  • Noticeable improvement in hair growth and thickness

What to Consider

  • Scent is somewhat strong

Type: Serum | Key Ingredients: Melatonin | Dosage: 1–2 mL up to twice daily | Cruelty-Free: Yes

Not only did this product deliver impressive results, but it was also incredibly easy—dare we say pleasant—to use. The serum-like consistency dried remarkably fast, swiftly absorbing into the scalp without leaving behind any unwanted residue. (We like that it's meant to be left on overnight, so you can apply it and forget it.)

After three months, our tester noticed more hair growth around her temples and noticeably improved fullness, particularly while sporting a ponytail. The key ingredient is melatonin, which has been shown to support regrowth and thicker strands after hair loss. We found the scent a little strong, but only upon initial application—it dissipates quickly.

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Taylor, tester with fine hair: "This was actually one of my favorite hair product applications. It's a dropper, which means I can put it right on my scalp, but the thing is, the product itself is almost dry, so it feels like it soaks into your scalp. Other products are more on the greasy side, so it feels like it sits on top of my hair…This [one] actually feels like it is penetrating my scalp."

What We Like

  • Affordable and accessible

  • Easy-to-use dropper

  • Yields visible results

What to Consider

  • Liquid formula is runny

  • Takes a while to dry on hair

Type: Leave-on serum | Key Ingredients: Minoxidil | Dosage: 1 mL twice daily | Cruelty-Free: Yes

Hair loss treatments aren't typically cheap, but this was the least expensive of all our winners. Still, it delivered noteworthy results. Our tester noticed a clear difference when looking at before-and-after pictures, particularly along her part, which is a common area for hair loss in women, according to double board-certified dermatologist Dr. Brendan Camp, M.D.

The dropper applicator was fairly easy to use, but the liquid formula does tend to run. While it dried quickly on the scalp, it took longer to dry on the hair, leaving it looking a bit wet and greasy before setting. Ultimately, we think this is a stellar deal for an effective hair loss treatment.

  • Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (4)

  • Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (5)

  • Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (6)

  • Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (7)

Shauna, tester with fine, wavy hair: "My hair definitely filled out more, and my part is more dense than it was. I have also noticed some new growth, which is great to see!"

What We Like

  • Encourages growth over bald spots

  • Dries quickly on hair and scalp

  • Doesn't cause irritation

What to Consider

  • Slightly drippy after spraying on hair

Type: Spray | Key Ingredients: Minoxidil | Dosage: Twice daily | Cruelty-Free: Yes

Hair loss doesn't look the same in men and women. According to Dr. Camp, women tend to see a widening part as a sign of hair loss, while men develop a bald spot at the top of the head. This pick is ideal for men dealing withbaldingthanks to its spray format that makes it easy to reach the back of the head. After 12 weeks of use, our tester noticed a layer of thinner hair covering balding areas (where there had previously been nothing). It also helped with thickness and fullness.

The leave-on liquid is meant to be sprayed twice daily, but this wasn't a problem largely because it is easy to use. It absorbs into the scalp within a few minutes without causing irritation and doesn't weigh the hair down. The only minor drawback is that the liquid consistency tends to run a bit, so you may want to keep a tissue handy to wipe off any drips.

Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (9)

Matt, tester with wavy hair, balding on top: "I was pleased with the hair growth I saw. It was fairly thick and uniform and not wispy or weird. My hair did appear thicker and fuller after the testing period."

What We Like

  • Noticeable results after one month

  • Improved hair growth and fullness

  • Doesn't cause irritation

What to Consider

  • Leaves scalp somewhat greasy

Type: Leave-on foam | Key Ingredients: Minoxidil | Dosage: Half-capful once daily | Cruelty-Free: Yes

Patience is a virtue when treating hair loss, which is one big reason we tested these products over 12 weeks. With that in mind, we were pleasantly surprised when our tester saw results just one month after starting this minoxidil foam. It helped fill in sparse spots on the scalp while improving the overall length, fullness, and general look and feel of the hair.

Our tester only used the foam once a day. However, it has to be measured into the product cap, a step our tester found inconvenient. While it didn't weigh down her strands, it left an unwanted sheen and greasy feel on the scalp. All that said, if you're looking for fast results, this product will deliver.

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Alexa, tester with very fine, wavy hair: "My hair looks overall longer, fuller, and healthier, and my scalp has definitely filled in."

What We Like

  • Doesn't cause irritation

  • Mousse-like formula stays in place

  • Dries in less than five minutes

What to Consider

  • Need to use twice daily

  • Takes a while to see results

Type: Leave-on foam | Key Ingredients: Minoxidil | Dosage: Half-capful twice daily | Cruelty-Free: Yes

Skin irritation is a common side effect of hair growth treatments, but using this foam twice daily for 12 weeks didn't cause any. However, it did result in new hair growth with twice-daily use. Our tester said it didn't cause any scalp tingling, nor did it have a scent (ideal for reactive skin).

It did take a while for results to kick in, but the product worked so well that it convinced our tester to keep using it. Our tester didn't love that it had to be applied two times a day, but for some, this is a small price to pay for visible improvement. Plus, the quick-drying foam was barely noticeable after applying.

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Robert, tester with coarse hair: "I've used Rogaine for years, and this seemed just as effective but less irritating to my scalp."

What We Like

  • Small applicator ideal for targeted areas

  • Noticeable new growth

  • Dries quickly

What to Consider

  • Lots of product needed per use

  • Pricier than others

Type: Leave-on spray | Key Ingredients: Minoxidil | Dosage: 6 sprays twice daily | Cruelty-Free: Yes

Sometimes, hair loss or thinning is only noticeable in small areas, such as along the hairline or at the roots. This formula is perfect for addressing those spots. For starters, the targeted nozzle makes precise application a breeze, something our tester greatly appreciated.

She used it to address hair loss along the hairline and temples, and about nine weeks into the testing period, she saw new baby hairs cropping up. Our tester wasn't thrilled about using six sprays of the product each time (and you must apply twice daily to see results). But the treatment dried quickly without weighing down the hair.

Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (15)

Allison, tester with fine, straight hair: "I have more baby hairs in the formerly sparse areas along my hairline and temples. They look like flyaways in photos, but it's new growth."

What We Like

  • No strong or irritating fragrance

  • Dries on scalp in seconds

  • Prevents existing hair loss from getting worse

  • Makes hair thicker and fuller

What to Consider

  • Hair must be dry before applying

  • Foam melts quickly in warm hands

Type: Leave-on foam | Key Ingredients: Minoxidil | Dosage: Half-capful twice daily | Cruelty-Free: No

If you're not into fragrances or have a sensitive scalp, this unscented option from Rogaine might be the one. Beyond being scent-free, the fast-drying foam absorbed quickly and never interfered with the look or feel of our tester's hair. He didn't see a ton of new hair growth but reported that the treatment made his existing hair thicker and fuller. It also slowed hair shedding (he saw way fewer hairs falling out in the sink).

Just a couple of things threw us about the application process. The foam can melt quickly (which is why the instructions say to apply with cold hands). And it requires some planning since your hair is supposed to be dry before each use. Still, this product seems to work—and with minoxidil, noticeable results often aren't visible until 24 or even 48 weeks.

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Peter, tester with coarse, straight hair: "My hairline never got worse, and I had dramatically fewer hairs falling out."

What We Like

  • Three products with detailed instructions

  • Improves thickness and fullness

  • Non-irritating formulas

What to Consider

  • Meant for daily hair-washing

Type: Shampoo, conditioner, leave-on foam | Key Ingredients: Minoxidil | Dosage: Once daily | Cruelty-Free: Yes

Consider this your one-stop shop for hair loss. The Virtue Flourish Kit includes shampoo, conditioner, and leave-on minoxidil foam. The latter is easy to use and effortlessly soaks into the skin—it was truly undetectable on the scalp. And it delivered real results. Not only was our tester's hair thicker and fuller, but she could also see improved growth, particularly along the edges.

There was no irritation or unwanted scent (great for our sensitive-skinned friends). Just keep in mind that if you don't wash your hair daily or even every other day, purchasing this set may not be the best use of funds.

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Chantia, tester with thick, kinky hair: "I have been avoiding doing ponytails for over a year now because my hair was heat-damaged, and my edges kept decreasing. However, I was able to get a ponytail two weeks ago, and even my stylist complimented the way I've been taking care of my hair—my edges are growing back thicker."

What We Like

  • Noticeable new growth and thickness

  • Liquid absorbs quickly

  • No scalp irritation

What to Consider

  • Not for color-treated hair

Type: Leave-on liquid | Key Ingredients: Minoxidil | Dosage: 1 mL twice daily | Cruelty-Free: No

Loss of hair volume and fullness can be frustrating—no one wants to pile on texturizing sprays constantly. Thankfully, this product restores fullness without product buildup. Our tester noticed a change in her hair about six weeks after starting the minoxidil-based leave-on serum. Some sparse patches began filling in, and she saw more fullness and length.

Though it did cause slight tingling upon application, there was never any irritation. One caveat, though: It's not ideal for color-treated hair. Our tester noticed her color fading and grays starting to re-emerge within a week.

Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (21)

Alisa, tester with thick, curly hair: "You have to be diligent in applying twice a day, but the results for me were worth it. My hair is fuller in the areas it was receding."

What We Like

  • Minimized shedding and overall hair loss

  • Triggers hair regrowth

  • Quick to apply

What to Consider

  • Can catch on hair before reaching scalp

  • Should be applied with cold hands to prevent melting

Type: Leave-on foam | Key Ingredients: Minoxidil | Dosage: Half-capful once daily | Cruelty-Free: No

While our tester saw some new hair growth with this product, she was more impressed by how it curtailed her existing hair loss and shedding during the testing period. The foam only has to be used once a day, at night—another attribute she appreciated—and it's fragrance-free.

However, as with many other winning foam formulas, it works best when applied with cold hands to avoid melting the mousse-like consistency. Also, it has a propensity to get stuck in the hair before you can really work it into the scalp, but after a few uses, you'll get the hang of it.

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Brenda, tester with fine, straight hair: "I liked that this is a once-a-day application, and I'm not losing as much hair daily as I was prior to using this product."

What We Like

  • Cleanses without stripping

  • Encourages new growth after shedding

  • Speeds up hair growth

What to Consider

  • Doesn't create sudsy lather

Type: Shampoo | Key Ingredients: Cannabidiol | Dosage: Once daily | Cruelty-Free: Yes

Vegamour Gro+ Advanced is the best hair-growth shampoo we've tested. After six weeks of consistent use, our tester's hair grew about a half-inch more than it typically would in a month and a half, and her baby hairs looked thicker. You'll want to let it sit for a minute before rinsing to allow the active ingredient, cannabidiol (CBD), to get to work. (CBD may help with hair loss by minimizing inflammation and regulating oil production on the scalp.)

This shampoo cleaned our tester's hair well without stripping it or causing irritation. We're also fans of the subtle citrusy-herbal scent. Since it's formulated without sulfates, it doesn't suds up into a rich later. But it still does its job and rinses out easily.

Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (25)

Roselynn, tester with thin, bleached hair: "My hair does seem fuller because of the volume and the new growth on my hairline also shows that it may help with hair thinning."

What to Consider When Buying Hair Loss Treatments

  • Cause of Hair Loss: Various factors can cause hair loss, such as genetics, hormones, nutrition, stress, etc., so we recommend first consulting with a dermatologist or trichologist to help you find the root cause (pun intended). "If hair loss is from stress, hormones, or nutrition, fixing the underlying issue (like managing stress or improving diet) is just as important," says board-certified dermatologist Dr. Omer Ibrahim, M.D. "[Hair loss treatments are] worth trying for early or mild cases, but if shedding is severe or persistent, a dermatologist is the way to go."
  • Product Type: There's a broad range of hair growth solutions on the market, from supplements you can take by mouth to thickening products you can apply topically—think hair oils, serums, foams, shampoos, conditioners, masks, etc. But again, it's best to identify the underlying cause before moving forward with a treatment plan.
  • Ingredients: The FDA only approves only one ingredient to help regrow hair: minoxidil. "Minoxidil is the only one clinically proven to regrow hair, but some other ingredients show promise," says Dr. Ibrahim. "If you're looking to strengthen hair and reduce shedding, ingredients like caffeine, peptides, niacinamide, and rosemary oil can support scalp health. DHT blockers (like saw palmetto) might help with hormonal hair loss. CBD is more about scalp health and reducing inflammation rather than actual regrowth."

How We Tested Hair Loss Treatments

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To find the best hair loss treatments that actually work, we first spoke to medical experts and used their advice to compile a list of 20 promising products. We then recruited testers across genders and hair types experiencing hair loss or thinning. Each tester used the product for 12 weeks, applying it according to the brand's instructions. They took photos of their hair and scalp before starting treatment and at the end of testing.

We also ensured the testers didn't get any hair treatments during the testing period, like haircuts or color, that could alter the look of their hair. After 12 weeks of consistent use, the testers rated the products based on:

  • Application: Consistency is key when using a hair loss treatment, so it's crucial the product is easy to use and not a burden. We noted if the application was messy, how quickly the products absorbed into the scalp, and how well the consistencies worked with specific hair textures.
  • Comfort: Hair loss treatments can feel tingly on the scalp, but we discarded any products that caused extreme irritation or discomfort. We also noted if the scent was bearable.
  • Performance: During the 12 weeks, testers consistently checked their scalps and recorded the moment they noticed any changes to their hair. At the end, they reported any visible signs of hair growth, using the "before" photo as a benchmark. We also noted those who saw less hair shedding than usual.
  • Value: Since hair loss treatments can be pricey, we rated the overall value of each product based on the results achieved after three months. Did we feel like the product delivered its promises and the results were worth the price? How long did the amount of the product last? Would we buy it again?

FAQ

  • What are the most common causes of hair loss?

    Inflammatory hair loss—the kind caused by stress, medications, and lifestyle factors—is common. It's also the most challenging to remedy because the exact cause varies. "This type of hair loss can be patchy, unpredictable, and associated with itching and burning," says trichologist William Gaunitz.

    A nutritional deficiency could also be an under-the-radar cause of hair loss. "Nutritional hair loss, in my opinion, is the most prominent form of hair loss worldwide and is also the most easily correctable," he says. "Nutritional hair loss causes general thinning throughout the entire scalp and can exacerbate other types of hair loss."

  • How can you prevent further hair loss?

    "Hair is very sensitive to inflammation, so it's important to avoid anything that irritates the scalp, such as certain hair dyes," says Dr. Pierre, adding that hot hair tools can also cause breakage. "You should condition your hair and moisturize your scalp regularly to minimize your chances of hair loss."

    As for nutrition, you can request a full blood panel from your healthcare provider to see if you're lacking in any essential nutrients. Gaunitz says the most critical for hair are iron, zinc, ferritin, folate, and vitamin D3.

  • How long does it take for hair loss treatments to work?

    Don't expect immediate, dramatic results from hair loss treatments. "Hair loss treatments take time—usually around four to six months to see real progress. Early signs that it’s working include less shedding, baby hairs growing in, or thicker strands overall," says Dr. Ibrahim. "Some treatments (like minoxidil) can cause initial shedding, which freaks people out, but that’s actually a sign that new growth is on the way." The key is consistency—be sure to follow the product's recommendation on how often to use it and don't skip doses or quit early, as any progress will likely reverse.

Meet Our Experts

For this story, Byrdie spoke to the following dermatologists and trichologists to better understand hair loss and the best treatments for it.

  • Dr. Peterson Pierre, M.D., is a board-certified dermatologist specializing in medical and cosmetic dermatology.
  • William Gaunitz, WTS, is a certified trichologist, founder of the Evolution Hair Loss Institute, and pioneer in natural hair regrowth treatments.
  • Dr. Omer Ibrahim, M.D., FAAD, is a board-certified dermatologist at Chicago Cosmetic Surgery and Dermatology.
  • Dr. Brendan Camp, M.D., is double board-certified in dermatology and dermatopathology and sees patients at MDCS Dermatology: Medical Dermatology & Cosmetic Surgery.

Why Trust Byrdie

Byrdie contributor Melanie Rud has over a decade of experience in the beauty industry, writing for some of the biggest magazines and websites out there. He has covered hair loss extensively during her career. (She’s also a new mom to twins experiencing postpartum shedding and trying new treatments to stop it.)

Emily Cieslak, an associate editor at Byrdie, interviewed several experts for this story.

Do Hair Loss Treatments Actually Work? We Found 11 Formulas That Gave Legit Results (2025)
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